Prometic Bioseparations Resource Library

Welcome to our resource Library, we hope you find something interesting to read, watch and share.

  • Endotoxin removal & β-D-Glucan Interference

    Endotoxin removal & β-D-Glucan Interference

    EtoxiClear™ has been shown to provide >3.4 log clearance of endotoxin from Fab fragments from an E. coli cell lysate, as well as from proteins such as IgG and HSA.

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  • EtoxiClear™: An novel affinity adsorbent for the efficient removal of endotoxin

    EtoxiClear™: An novel affinity adsorbent for the efficient removal of endotoxin

    A number of methods have been adopted for the removal of endotoxin based on adsorption, in particular ion-exchange chromatography.

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  • Capture and purification of human serum albumin from human source plasma using Mimetic Blue® SA HL P6XL

    Capture and purification of human serum albumin from human source plasma using Mimetic Blue® SA HL P6XL

    In this application note we describe how human serum albumin is captured and purified from human source plasma using Mimetic Blue® SA HL P6XL.

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  • Capture and purification of recombinant albumin-fusion proteins using AlbuPure®.

    Capture and purification of recombinant albumin-fusion proteins using AlbuPure®.

    AlbuPure® can be used to capture and purify recombinant albumin-fusion proteins from cell culture supernatants with high purity and recovery.

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  • Endotoxin Removal from Bench to Process Scale.

    Endotoxin Removal from Bench to Process Scale.

    Endotoxin or lipopolysaccharides (LPS) are highly toxic components of the cell wall of Gram-negative bacteria and are often present in significant amounts in bacterial cell expression systems.

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  • Immobilised Boronate Ligand Affinity Adsorbents for Glycoproteins

    Immobilised Boronate Ligand Affinity Adsorbents for Glycoproteins

    The most important application the adsorbent is as a general method for separation and purification of glycosylated from non-glycosylated proteins and often from other forms of glycosylated proteins.

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  • Multi-Mode Mimetic Ligand™ Library - a New Tool for Adsorbent Screening and Selection

    Multi-Mode Mimetic Ligand™ Library - a New Tool for Adsorbent Screening and Selection

    In response to a growing demand for rapid bioprocess development tools, Prometic has launched a new, easy to screen, library of multi-mode Mimetic Ligand™ adsorbents.

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  • Poster: Multi Mode Mimetic Ligand™ Library

    Poster: Multi Mode Mimetic Ligand™ Library

    Prometic have developed a cost effective, easy to use, rapid ‘screening toolbox’ for target protein purification - Multi-Mode Mimetic Ligand™ Library.

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  • Article: Disposable Column options

    Article: Disposable Column options

    Over the last couple of years, interest has been growing in the use of pre-packed disposable chromatography columns and in the use of disposable process fluid contact pathways.

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