Activation of the Free-Fatty Acid Receptor GPR40 Improves Anemia in Mouse Models of Kidney Disease via a Novel EPO-Independent Mechanism of

October 25, 2018
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PBI-4050 reduces systemic inflammation, electrolyte disturbances and renal injury in mice with sepsis-induced acute kidney injury
PBI-4050 reduces systemic inflammation, electrolyte disturbances and renal injury in mice with sepsis-induced acute kidney injury

PBI-4050 exerts anti-inflammatory and anti-fibrotic effects in several diabetic and non-diabetic models of ...

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PBI-4050 decreases adenine-induced tubulointerstitial injury and er-stress; implications of the GPR40 receptor
PBI-4050 decreases adenine-induced tubulointerstitial injury and er-stress; implications of the GPR40 receptor

The aim of this study was to further examine the effects of PBI-4050 in both WT and GPR40 activation-/- mic...