PBI-4547 Prevents Progression of Prediabetic Condition to Type 1 Diabetes in NOD Mice

June 22, 2018

PBI-4547 administration in prediabetic type 1 NOD mice significantly prevented the evolution to severe diabetes resulting in increased survival. This obviously results from increased insulin production and secretion by remaining B-cells in the islets of Langherhans.

These results suggest that PBI-4547 offers the potential as a novel therapy for the treatment of type 1 diabetes. 

No Previous Flipbooks

Next Flipbook
PBI-4547 Improves Glucose Metabolism and Insulin Resistance, and Reduces Liver Damage in a High-Fat Diet Mouse Model of Obesity and Metaboli
PBI-4547 Improves Glucose Metabolism and Insulin Resistance, and Reduces Liver Damage in a High-Fat Diet Mouse Model of Obesity and Metaboli

Taken together, these results suggest that PBI-4547 offers the potential as a novel therapy for Non-alcohol...